Last updated on May 26, 2022. Steven Gans, MD, is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. digestive side effects, including constipation and nausea*. The brand name Wellbutrin has been discontinued, but bupropion is still available as a generic for depression. Ewwwhat's that odor? If you notice other effects not listed above, contact your doctor or pharmacist. DOI: DeVere R. (2012). Wellbutrin XL: Highlights of prescribing information. health information, we will treat all of that information as protected health irritation from smoking or poor air quality. In animal studies, there has been some evidence of adverse effects on the fetus, but we don't yet have enough data about its effect on humans. constipation joint pain dizziness difficulty sleeping excessive sweating muscle tremors decreased appetite weight loss headache heart throbbing or pounding nausea diarrhea nervousness intense. To ensure proper treatment, Wellbutrin needs to be taken on a consistent schedule. A systematic review of the use of bupropion for hypoactive sexual desire disorder in premenopausal women. Taking more than the recommended dose of bupropion may increase your risk of having a seizure. Wellbutrin XL (bupropion hydrochloride) extended-release tablets. By contrast, Wellbutrin is thought to act by influencing levels of the neurotransmitters norepinephrine and dopamine. Mayo Clinic does not endorse any of the third party products and services advertised. It is intended to be used alongside diet and exercise. More likely than other antidepressants to cause weight loss; however, may also cause weight gain in some people. All rights reserved. DOI: Landis BN, et al. UHN Premier Pass is your online passport to the full resources of University Health News! Consult your pharmacist or local waste disposal company. In rare cases, Wellbutrin can cause dangerously high blood pressure or liver failure. Changes in smell or taste Changes include loss, decreased, increased or unpleasant changes in smell or taste. When this happens, its sometimes called an olfactory hallucination. To help you remember, use it at the same times each day. This risk is increased with higher dosages of Wellbutrin, in those with head injuries or taking other medications which also lower the seizure threshold. Zyban, Aplenzin, Forfivo XL, Budeprion SR, +2 more. Speak to your doctor about how drug interactions should be managed. Wellbutrin, used for the treatment of MDD, is available as 75-milligram (mg) and 100-mg tablets. Avoid performing hazardous tasks such as driving if Wellbutrin has this effect on you. Insomnia, headache, dizziness, dry mouth, sore throat, nausea, and constipation were the more commonly reported side effects. This can affect the levels of Wellbutrin and its metabolites in your bloodstream. Wellbutrin SR (sustained-release), used for the treatment of MDD, is available as 100-mg and 150-mg tablets. Talk with your healthcare provider if youre concerned about side effects and notice any that are interfering with your day-to-day life. (2008). If you are planning pregnancy, become pregnant, or think you may be pregnant, immediately discuss with your doctor the benefits and risks of using this medication during pregnancy. Select a condition to view a list of medication options. This content does not have an Arabic version. How to Stop Taking SSRI Antidepressants Safely, What to Know About Cipralex (Escitalopram), Wellbutrin Withdrawal: Overview, Symptoms & Coping, Wellbutrin for Bipolar Disorder: Risks and Benefits. If you have phantosmia, the odors can vary from smells that almost make you sick to really pleasant scents. National Alliance on Mental Illness. If its sinusitis, you treat it with antibiotics., In some cases, the phantom smell is idiopathic, meaning it has no known cause. With UHN Premier Pass you'll have unlimited online access to all six of our monthly Health Newsletters, plus so much more. The reason? These include: While the most common smells associated with phantosmia tend to be undesirable, some people do report smelling sweet or pleasant odors. It is important to take your doses at least 6 hours apart or as directed by your doctor to decrease your risk of having a seizure. Healthline Media does not provide medical advice, diagnosis, or treatment. Drug class: miscellaneous antidepressants, https://www.drugs.com/pro/wellbutrin.html. Medically reviewed by Carmen Fookes, BPharm. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Wellbutrin may be used in the treatment of depression; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. Healthline only shows you brands and products that we stand behind. Sometimes it affects the way something tastes. Most people only experience impaired taste. If you happen to miss a dose of bupropion, take it as soon as you remember. antiarrhythmics, such as amiodarone or flecainide, anticonvulsants, such as carbamazepine, phenytoin, phenobarbital, or primidone, antidepressants, such as SSRIs (eg, fluoxetine, sertraline), tricyclic antidepressants (such as desipramine, nortriptyline), or MAOIs (such as phenelzine or selegiline), antipsychotics (such as butyrophenones, phenothiazines, or thioxanthenes) and atypical antipsychotics (eg, olanzapine, quetiapine, ziprasidone), any medication that lowers the seizure threshold, such as tramadol, reserpine, and volatile anesthetics, beta-blockers, such as atenolol or metoprolol, blood thinners, such as clopidogrel or ticlopidine, corticosteroids, such as prednisone or methylprednisone, HIV medications, such as ritonavir or lopinavir, Wellbutrin (bupropion) (Package Insert). It caused my hypersensitivity to perfumes/chemicals,etc. The air is coming in through the nose and its being processed as a smell, Hirsch explains. By inhibiting serotonin reuptake, SSRIs help increase active serotonin levels in the brain, improving moodand anxiety. Causes include a head injury, brain tumor, Parkinsons disease, upper respiratory infection, and inflamed sinuses. A well-functioning sense of smell is something most people take for granted, until its lost. information highlighted below and resubmit the form. I have been on Wellbutrin for a couple of years and I have definitely noticed an increased sense of smell which has affected me quite a bit! Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use wellbutrin only for the indication prescribed. It is also used off-label to help with symptoms of various other conditions. The symptoms of these disorders include the following. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Commonly reported phantom smells are bad, such as rotten eggs or burning hair. (2015). Yes. Different Types of Depression: An Overview, Symptoms of a severe allergic reaction include, Wellbutrin XL: Highlights of prescribing information, A systematic review of the use of bupropion for attention-deficit/hyperactivity disorder in children and adolescents, A systematic review of the use of bupropion for hypoactive sexual desire disorder in premenopausal women, Wellbutrin (bupropion hydrochloride) tablets, What are the symptoms of high blood pressure, ACOG guidelines on psychiatric medication use during pregnancy and lactation, Attention deficit hyperactivity disorder (ADHD), Have a known hypersensitivity to bupropion or any inactive ingredient in Wellbutrin, Have recently stopped taking drugs like benzodiazepine, anticonvulsants, and barbiturates, or consuming alcohol, all of which can trigger seizures, Have a prior history of anorexia or bulimia (because it can increase the risk of seizures), Are taking monoamine oxidase inhibitors (MAOIs; there is a risk of a drug interaction). Its a thing. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Wellbutrin 75 Mg Tablet side effects by likelihood and severity. All formulations can be stored safely at room temperature (up to 77 degrees F). Accessed May 23, 2022. the unsubscribe link in the e-mail. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Each tablet contains the labeled amount of bupropion hydrochloride and the inactive ingredients: 75-mg tablet - D&C Yellow No. So I have to ask my husband if it tastes weird. Such odors as smoke, gas and rotten food, for instance, could be mistaken or ignored. If any of these effects last or get worse, notify your doctor or pharmacist promptly. An olfactory hallucination (phantosmia) makes you detect smells that aren't really there in your environment. National Alliance on Mental Illness. Always tell your healthcare provider about the medications and anything else youre taking, including prescription or over-the-counter drugs, nutritional or herbal supplements, and recreational drugs. Stopping abruptly can also lead todiscontinuation syndrome, an array of flu-likesymptoms such as stomach upset, headache, strange sensations, and muscle aches. 2017;10:CD009504. The phantom smell may seem to always be there or it may come and go. Available for Android and iOS devices. I've been taking Wellbutrin for three months 150mg extended release. You may opt-out of email communications at any time by clicking on Selected from data included with permission and copyrighted by First Databank, Inc. Your dosage may need to be changed or the medication switched to ease these effects. In some cases, such as in people with severe liver or kidney disease, the dose of Wellbutrin may need to be adjusted. The medical term used to describe phantom smells is phantosmia, a disorder also known as an olfactory hallucination. This survey is being conducted by the WebMD marketing sciences department. Wellbutrin can also affect the central nervous system and motor function. Types and causes of smell disorders The causes of smell disorders are not well understood, but women seem to. Wellbutrin 75 Mg Tablet. It definitely helps me. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your dose may need to be gradually decreased. If you have any questions about how to take the drug, ask your pharmacist or healthcare provider. Metallic smells, cooked food, and dusty or dirty odors were also noted. Do not start, stop, or change the dosage of any medicines without your doctor's approval. DOI: Malaty A, et al. dental problems. Wellbutrin SR. American Heart Association. Phantosmia may be caused by a head injury or upper respiratory infection. I have a very keen sense of smell but today it seems I can smell everything -- my son's BO, my dog's medicine, my basement -- all much more intense than ever before. Accessed May 23, 2022. J Am Coll Cardiol. Lafreniere D. Taste and olfactory disorders in adults: Anatomy and etiology. Phantosmia: What causes olfactory hallucinations? Seek immediate medical advice if any changes are apparent. If these exams dont point to a specific cause, you may need an MRI scan or CT scan to rule out any neurological conditions, such as Parkinsons disease. Note: See a doctor if youre constantly noticing a phantom smell, or if you notice a loss of smell. Most often, these phantom smells are unpleasant (e.g., burning hair, sewage, or cigarette smoke). Drugs that can potentially interact with Wellbutrin include: U.S. Food and Drug Administration. Your healthcare provider can help you weigh the benefits and risks of taking Wellbutrin. Your healthcare provider may prescribe a modified dosage of Wellbutrin due to possible side effects or another health concern. The phantom smell you experience could tell you something about your health, says Alan Hirsch, MD, of the Smell & Taste Treatment and Research Foundation. Mostly smells however. Shandley also has authored numerous articlesRead More. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. People with major depression have several of these symptoms for at least two weeks: Seasonal MDD: A major depressive episode with the symptoms above that also consistently recurs at particular times during the year, usually during the dark winter months. Report side effects, including constipation and nausea * loss ; however, may also weight! Research ( MFMER ) not listed above, contact your doctor 's approval it may come and go symptoms various... Of the use of bupropion for hypoactive sexual desire disorder in premenopausal women well-functioning sense of smell are!, identify pills, check interactions and set up your own personal medication records blood pressure or liver failure to! But bupropion is still available as a smell, or cigarette smoke ) allergic to ;... 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